Enabling WP_DEBUG will cause all PHP errors, notices and warnings to be displayed. This is likely to modify the default behavior of PHP which only displays fatal errors and/or shows a white screen of death when errors are reached.
Showing all PHP notices and warnings often results in error messages for things that don’t seem broken, but do not follow proper data validation conventions inside PHP. These warnings are easy to fix once the relevant code has been identified, and the resulting code is almost always more bug-resistant and easier to maintain.